Fecal transplant — sometimes called a poop transplant, stool transplant, or FMT — restores the gut microbiome by transferring screened donor stool. It is the most effective therapy known for recurrent C. difficile, and it is being studied in conditions from ulcerative colitis to depression.
The only condition for which FMT is FDA-recognised. Cure rates of 85–95% after multiply-recurrent CDI.
Multiple randomised trials show FMT can induce remission in a meaningful subset of patients.
Open-label trials report sustained gastrointestinal and behavioural improvements two years after treatment.
Small pilot studies probing the gut–brain axis suggest improvements in depressive and anxiety symptoms.